Gait and behavior in an IL1β-mediated model of rat knee arthritis and effects of an IL1 antagonist
نویسندگان
چکیده
منابع مشابه
Gait and behavior in an IL1β-mediated arthritis model and effects of IL1 antagonism Gait and Behavior in an IL-1β-Mediated Model of Rat Knee Arthritis and Effects of an IL1 Antagonist
250 Word Limit) Objective: Interleukin-1 beta (IL1β) is a pro-inflammatory cytokine that mediates arthritic pathologies. Our objective was to evaluate pain and limb dysfunction resulting from IL1β overexpression in the rat knee and investigate the ability of local IL1 receptor antagonist (IL1Ra) delivery to reverse associated pathology. Design: IL1β over-expression was induced in the right knee...
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ژورنال
عنوان ژورنال: Journal of Orthopaedic Research
سال: 2010
ISSN: 0736-0266
DOI: 10.1002/jor.21309